News
2025.10.10
[Article] Deep learning identifies TP-41 for methylglyoxal scavenging in Alzheimer’s treatment, Theranostics (IF =13.2), Published
2025.09.29
[Article] The Causal Relationship of Multiple Sclerosis on Serum Uric Acid Levels: A Mendelian Randomization Study, OMICS: A Journal of Integrative Biology,(IF=1.6), Published
2025.09.05
[Article] Acute Hyperinsulinemia during Hyperinsulinemic- Euglycemic Clamp Influences DNA Methylation and Gene Expression in Peripheral Blood Cells of Adult Men, Diabetes and Metabolism Journal,(IF=8.5), Published
2025.02.27
[Article] Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single-cell RNA sequencing analysis, Molecular Oncology,(IF=4.5), Published
2024.07.19
[Article] Adolescent gut microbiome imbalance and its association with immune response in inflammatory bowel diseases and obesity, BMC Microbiology, (IF=4.0), Published.
2024.06.28
[Article] The causal relationship of serum uric acid on colorectal cancer: A Mendelian randomization study, Medicine, (IF=1.89), Published.
2024.02.23
[Article] Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration, Biomaterials Research, (IF=11.3), Published.
2024.01.17
[Article]Inhibition of SIRT7 overcomes sorafenib acquired resistance by suppressing ERK1/2 phosphorylation via the DDX3X-mediated NLRP3 inflammasome in hepatocellular carcinoma, Drug Resistance Updates, (IF=24.3), Published.
2023.11.06
[Article] Characterization of the genomic alterations in poorly differentiated thyroid cancer, Scientific reports, (IF=4.6), Published.
2023.10.06
[Article] The causal relationship of colorectal cancer on schizophrenia: A Mendelian randomization study, Medicine, (IF=1.89), Published.
2023.10.05
[Article] Network and Computational Drug Repurposing Analysis for c-Myc Inhibition in Burkitt Lymphoma, Cancer Genomics & Proteomics, (IF=3.395), Accepted.
2023.08.22
[Article] miRDM-rfGA: Genetic Algorithm-Based Identification of a MiRNA Set for Detecting Type 2 Diabetes, BMC medical genomics, (IF=2.7), Published.
2023.08.04
[Article] Urban dust particles disrupt mitotic progression by dysregulating Aurora kinase B-related functions, Journal of Hazardous Materials, (IF=13.6), Published.
2023.07.24
[Article] A performance evaluation of drug response prediction models for individual drugs, Scientific reports, (IF=4.6), Published.
Journal Club
2026.01.28
Dauparas J, Lee GR, Pecoraro R, et al. Atomic context-conditioned protein sequence design using LigandMPNN. Nat Methods. 2025;22(4):717-723. doi:10.1038/s41592-025-02626-1.
2025.12.24
Senior AW, Evans R, Jumper J, et al. Improved protein structure prediction using potentials from deep learning. Nature. 2020;577(7792):706-710. doi:10.1038/s41586-019-1923-7.
2025.12.17
Jumper, John, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, et al. 2021. Highly accurate protein structure prediction with AlphaFold. Nature. Springer Science and Business Media LLC, 15. July. doi:10.1038/s41586-021-03819-2,
2025.11.26
Wang T, Holscher HD, Maslov S, Hu FB, Weiss ST, Liu Y-Y. Predicting metabolite response to dietary intervention using deep learning. Nat Commun. 2025;16(1). doi:10.1038/s41467-025-56165-6.
2025.11.19
Lu MY, Chen B, Williamson DFK, et al. A visual-language foundation model for computational pathology. Nat Med. 2024;30(3):863-874. doi:10.1038/s41591-024-02856-4
2025.09.21
Binyamin D, Turjeman S, Asulin N, Schweitzer R, Koren O. The microbiome is associated with obesity-related metabolome signature in the process of aging. npj Biofilms Microbiomes. 2025;11(1). doi:10.1038/s41522-025-00811-w.
2025.08.20
Lai C, Yin M, Kholmovski EG, et al. Multimodal AI to forecast arrhythmic death in hypertrophic cardiomyopathy. Nat Cardiovasc Res. 2025;4(7):891-903. doi:10.1038/s44161-025-00679-1
2025.07.02
Abramson J, Adler J, Dunger J, et al. Accurate structure prediction of biomolecular interactions with AlphaFold 3. Nature. 2024;630(8016):493-500. Nature. doi:10.1038/s41586-024-07487-w
2025.03.19
Hayes T, Rao R, Akin H, et al. Simulating 500 million years of evolution with a language model. Science. 2025;387(6736):850-858.Science. doi:10.1126/science.ads0018
2025.02.12
Brandes N, Ofer D, Peleg Y, et al. (2022 Apr 12) ProteinBERT: a universal deep-learning model of protein sequence and function. Bioinformatics. doi:10.1093/bioinformatics/btac020
2025.01.22
Xiang J, Wang X, Zhang X, et al. (2025 Jan 8). A vision-language foundation model for precision oncology. Nature. doi: 10.1038/s41586-024-08378-w.
2024.12.18
Matusiak M, Hickey JW, et al. (2024 Aug 2). Spatially Segregated Macrophage Populations Predict Distinct Outcomes in Colon Cancer. Cancer Discov. doi: 10.1158/2159-8290.CD-23-1300
2024.11.21
Krapp LF, Abriata LA, et al. (2023 Apr 18). PeSTo: parameter-free geometric deep learning for accurate prediction of protein binding interfaces. Nat Commun. doi:10.1038/s41467-023-37701-8
2024.11.13
Vanrobaeys Y., Mukherjee U., et al. (2023 Sep 29). Mapping the spatial transcriptomic signature of the hippocampus during memory consolidation. Nat Commun. doi:10.1038/s41467-023-41715-7
2024.11.06
Love NR, Williams C, Killingbeck EE, et al. (2024 Jul 12). Melanoma progression and prognostic models drawn from single-cell, spatial maps of benign and malignant tumors. Sci Adv. doi:10.1126/sciadv.adm8206
2024.09.11
Park H, Cho B, Kim H, et al. (2023 Feb 13). Single-cell RNA-sequencing identifies disease-associated oligodendrocytes in male APP NL-G-F and 5XFAD mice. Nat Commun. doi:10.1038/s41467-023-36519-8
2024.08.27
Mallach A, Zielonka M, et al. (2024 Jun 25). Microglia-astrocyte crosstalk in the amyloid plaque niche of an Alzheimer's disease mouse model, as revealed by spatial transcriptomics. Cell Rep. doi:10.1016/j.celrep.2024.114216