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2024

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  1. Kwak, Sojung, Cho Lok Song, Jinhyuk Lee, Sungyeon Kim, Seungyoon Nam, Young-Jun Park and Jungwoon Lee. 2024. Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration. Biomaterials. Elsevier BV, February. doi:10.1016/j.biomaterials.2024.122522

  2. Kim, Yuna, Kwan-Young Jung, Yun Hak Kim, Pan Xu, Baeki E. Kang, Yunju Jo, Navin Pandit, et al. 2024. Inhibition of SIRT7 overcomes sorafenib acquired resistance by suppressing ERK1/2 phosphorylation via the DDX3X-mediated NLRP3 inflammasome in hepatocellular carcinoma. Drug Resistance Updates. Elsevier BV, March. doi:10.1016/j.drup.2024.101054

2023

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  1. Shin, Seung Kak, Sujin Ryu, Seungyoon Nam, Seung Yeon Ha, Oh Sang Kwon, Yun Soo Kim, Se-Hee Kim and Ju Hyun Kim. 2023. Clinical Significance of Combined Epithelial–Mesenchymal Transition Markers Expression and Role of Rac1 in Hepatocellular Carcinoma. International Journal of Molecular Sciences. MDPI AG, 16. January. doi:10.3390/ijms24021765

  2. Moon, SeongRyeol, Hee Joo Kim, Yeeun Lee, Yu Joo Lee, Sungwon Jung, Jin Sook Lee, Si Houn Hahn, Kyungdoc Kim, Joo Young Roh and Seungyoon Nam. 2023. Oncogenic signaling pathways and hallmarks of cancer in Korean patients with acral melanoma. Computers in Biology and Medicine. Elsevier BV, March. doi:10.1016/j.compbiomed.2023.106602

  3. Ji, Su Min, Jae-Sun Choi, Ji Young Lee, Sungyeon Kim, Woom-Yee Bae, Ye Won Jang, Ja-Eun Kim, Seung Hyeun Lee, Seungyoon Nam and Joo-Won Jeong. 2023. Mild exposure to fine particulate matter promotes angiogenesis in non-small cell lung carcinoma. Environmental Pollution. Elsevier BV, July. doi:10.1016/j.envpol.2023.121715

  4. Park, Aron, Yeeun Lee and Seungyoon Nam. 2023. A performance evaluation of drug response prediction models for individual drugs. Scientific Reports. Springer Science and Business Media LLC, 24. July. doi:10.1038/s41598-023-39179-2

  5. Park, Aron and Seungyoon Nam. 2023. miRDM-rfGA: Genetic algorithm-based identification of a miRNA set for detecting type 2 diabetes. BMC Medical Genomics. Springer Science and Business Media LLC, 22. August. doi:10.1186/s12920-023-01636-2, doi:10.1186/s12920-023-01636-2.

  6. Kim, Sungyeon and Seungyoon Nam. 2023. The causal relationship of colorectal cancer on schizophrenia: A Mendelian randomization study. Medicine. Ovid Technologies (Wolters Kluwer Health), 6. October. doi:10.1097/md.0000000000035517, doi:10.1097/md.0000000000035517.

  7. Ryu, Jaewook, Seung Hyeun Lee, Sungyeon Kim, Joo-Won Jeong, Kyung Sook Kim, Seungyoon Nam and Ja-Eun Kim. 2023. Urban dust particles disrupt mitotic progression by dysregulating Aurora kinase B-related functions. Journal of Hazardous Materials. Elsevier BV, October. doi:10.1016/j.jhazmat.2023.132238.

  8. Lee, Yeeun, SeongRyeol Moon, Jae Yeon Seok, Joon-Hyop Lee, Seungyoon Nam and Yoo Seung Chung. 2023. Characterization of the genomic alterations in poorly differentiated thyroid cancer. Scientific Reports. Springer Science and Business Media LLC, 6. November. doi:10.1038/s41598-023-46466-5.

2022

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  1. Nam, Seungyoon, Sungyoung Lee, Sungjin Park, Jinhyuk Lee, Aron Park, Yon Hui Kim and Taesung Park. 2021. PATHOME-Drug: a subpathway-based polypharmacology drug-repositioning method. Ed. by Can Alkan. Bioinformatics. Oxford University Press (OUP), 13. September. doi:10.1093/bioinformatics/btab566

  2. Park, Aron, Minjae Joo, Kyungdoc Kim, Won-Joon Son, GyuTae Lim, Jinhyuk Lee, Jung Ho Kim, Dae Ho Lee and Seungyoon Nam. 2022. A comprehensive evaluation of regression-based drug responsiveness prediction models, using cell viability inhibitory concentrations (IC50 values). Ed. by Jinbo Xu. Bioinformatics. Oxford University Press (OUP), 23. March. doi:10.1093/bioinformatics/btac177

  3. Park, Aron, Seung Joon Choi, Sungjin Park, Seong Min Kim, Hye Eun Lee, Minjae Joo, Kyoung Kon Kim, et al. 2022. Plasma Aldo-Keto Reductase Family 1 Member B10 as a Biomarker Performs Well in the Diagnosis of Nonalcoholic Steatohepatitis and Fibrosis. International Journal of Molecular Sciences. MDPI AG, 1. May. doi:10.3390/ijms23095035

  4. Nam, Seungyoon and Yongmin Lee. 2022. Genome-Scale Metabolic Model Analysis of Metabolic Differences between Lauren Diffuse and Intestinal Subtypes in Gastric Cancer. Cancers. MDPI AG, 9. May. doi:10.3390/cancers14092340

  5. Choi, Minseok, SeongRyeol Moon, Hyo Jin Eom, Seung Mook Lim, Yon Hui Kim and Seungyoon Nam. 2022. High Expression of PRNP Predicts Poor Prognosis in Korean Patients with Gastric Cancer. Cancers. MDPI AG, 28. June. doi:10.3390/cancers14133173

  6. Park, Sungjin, Jungsuk An, Seung Yeon Ha, Seungyoon Nam and Jung Ho Kim. 2022. Immune signature as a potential marker for predicting response to immunotherapy in obesity‐associated colorectal cancer. Journal of Gastroenterology and Hepatology. Wiley, 22. June. doi:10.1111/jgh.15909

  7. Park, Sungjin, Ok-Hee Kim, Kiyoung Lee, Ie Byung Park, Nan Hee Kim, Seongryeol Moon, Jaebeen Im, et al. 2022. Plasma and urinary extracellular vesicle microRNAs and their related pathways in diabetic kidney disease. Genomics. Elsevier BV, July. doi:10.1016/j.ygeno.2022.110407

  8. Beak, Myeonghun, Sungjin Park, Jin-Hee Kim, Hyo Jin Eom, Ho-Yeon Lee, Yon Hui Kim, Jinhyuk Lee and Seungyoon Nam. 2022. Second-Generation JK-206 Targets the Oncogenic Signal Mediator RHOA in Gastric Cancer. Cancers. MDPI AG, 22. March. doi:10.3390/cancers14071604

  9. Nam, Seungyoon, Yeeun Lee and Jung Ho Kim. 2022. RHOA protein expression correlates with clinical features in gastric cancer: a systematic review and meta-analysis. BMC Cancer. Springer Science and Business Media LLC, 19. July. doi:10.1186/s12885-022-09904-7

  10. Na, Yewon, Soo Wan Kim, Ie Byung Park, Soo Jung Choi, Seungyoon Nam, Jaehun Jung and Dae Ho Lee. 2022. Association Between DPP4 Inhibitor Use and the Incidence of Cirrhosis, ESRD, and Some Cancers in Patients With Diabetes. The Journal of Clinical Endocrinology & Metabolism. The Endocrine Society, 15. September. doi:10.1210/clinem/dgac540

  11. Kang, Baeki E., Aron Park, Hyekyung Yang, Yunju Jo, Tae Gyu Oh, Seung Min Jeong, Yosep Ji, et al. 2022. Machine learning-derived gut microbiome signature predicts fatty liver disease in the presence of insulin resistance. Scientific Reports. Springer Science and Business Media LLC, 17. December. doi:10.1038/s41598-022-26102-4

2021

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  1. ​Bae, Woom-Yee, Jae-Sun Choi, Seungyoon Nam and Joo-Won Jeong. 2021. β-arrestin 2 stimulates degradation of HIF-1α and modulates tumor progression of glioblastoma. Cell Death & Differentiation. Springer Science and Business Media LLC, 18. May. doi:10.1038/s41418-021-00802-2

  2. Lee, Yeeun and Seungyoon Nam. 2021. Performance Comparisons of AlexNet and GoogLeNet in Cell Growth Inhibition IC50 Prediction. International Journal of Molecular Sciences. MDPI AG, 19. July. doi:10.3390/ijms22147721
     

2020

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  1. Bong, Seoung Min, Seung-Hyun Bae, Bomin Song, HyeRan Gwak, Seung-Won Yang, Sunshin Kim, Seungyoon Nam, et al. 2020. Regulation of mRNA export through API5 and nuclear FGF2 interaction. Nucleic Acids Research. Oxford University Press (OUP), 8. May. doi:10.1093/nar/gkaa335

  2. Han, Sanghoon, Sungjin Park, Jungsuk An, Jun-Young Yang, Jun-Won Chung, Yoon Jae Kim, Kyoung Oh Kim, et al. 2020. HER2 as a potential biomarker of lymph node metastasis in undifferentiated early gastric cancer. Scientific Reports. Springer Science and Business Media LLC, 24. March. doi:10.1038/s41598-020-61567-1

  3. Kim, Jin-Hee, Sungjin Park, Seung Mook Lim, Hyo Jin Eom, Curt Balch, Jinhyuk Lee, Gi Jin Kim, Jin-Hyun Jeong, Seungyoon Nam and Yon Hui Kim. 2020. Rational design of small molecule RHOA inhibitors for gastric cancer. The Pharmacogenomics Journal. Springer Science and Business Media LLC, 4. February. doi:10.1038/s41397-020-0153-6

  4. Moon, SeongRyeol, Junbae Oh and Seungyoon Nam. 2020. Linear programming-based prediction of immune cell composition. International Journal of Data Mining and Bioinformatics. Inderscience Publishers. doi:10.1504/ijdmb.2020.107382

  5. Park, Sungjin, Kiyoung Lee, Ie Byung Park, Nan Hee Kim, Seongcheol Cho, Won Jong Rhee, Yujin Oh, Jimin Choi, Seungyoon Nam and Dae Ho Lee. 2020. The profiles of microRNAs from urinary extracellular vesicles (EVs) prepared by various isolation methods and their correlation with serum EV microRNAs. Diabetes Research and Clinical Practice. Elsevier BV, February. doi:10.1016/j.diabres.2020.108010

2019

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  1. Minjae Joo, Aron Park, Kyungdoc Kim, Won-Joon Son, Hyo Sug Lee, GyuTae Lim, Jinhyuk Lee, Dae Ho Lee, Jungseok An, Jung Ho Kim, TaeJin Ahn, Seungyoon Nam A Deep Learning Model for Cell Growth Inhibition IC50 Prediction and Its Application for Gastric Cancer Patients Int. J. Mol. Sci. 2019, 20(24), 6276; DOI: 10.3390/ijms20246276, 12 December 2019

  2. Sungjin Park, Hee Kyung Ahn, Dae Ho Lee, YunJae Jung, Joo-Won Jeong, Seungyoon Nam & Won-Suk Lee Systematic mutation analysis in rare colorectal cancer presenting ovarian metastases Scientific reports 9.1 (2019): 1-10, Article number: 16990 (2019) DOI: 10.1038/s41598-019-53182-6, 18 November 2019

  3. Sungjin Park, SeongRyeol Moon, Kiyoung Lee, Ie Byung Park, Dae Ho Lee, Seungyoon Nam miR2Diabetes: A Literature-Curated Database of microRNA Expression Patterns, in Diabetic Microvascular Complications Genes (Basel). 2019 Oct; 10(10): 784 DOI: 10.3390/genes10100784, 9 October 2019

  4. Eun Sook Ryu, Seung Jun Chang, Jungsuk An, Jun-Young Yang, Jun-Won Chung, Yoon Jae Kim, Kyoung Oh Kim, Dong Kyun Park, Kwang An Kwon, Seungyoon Nam , Woon Kee Lee, Jung Ho Kim Sex-specific differences in risk factors of lymph node metastasis in patients with early gastric cancer. PLoS One. 2019;14(10):e0224019. DOI: 10.1371/journal.pone.0224019, 18 Oct 2019

  5. Aron Park, Seungyoon Nam Deep learning for stage prediction in neuroblastoma using gene expression data Genomics Inform. 2019;17(3):e30  Published online September 27, 2019 DOI: 10.5808/GI.2019.17.3.e30, 27 September 2019

  6. Ara Cho, Se-Ra Park, Soo-Rim Kim, Seungyoon Nam, Soyi Lim, Chan Hum Park, Hwa-Yong Lee, In-Sun Hong, An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through SERPINB2, Molecular Therapy, Volume 27, Issue 7, 2019, Pages 1286-1298, ISSN 1525-0016, DOI: 10.1016/j.ymthe.2019.04.019, 3 July 2019

  7. Seungyoon Nam, Jung Ho Kim, Dae Ho Lee RHOA in Gastric Cancer: Functional Roles and Therapeutic Potential Front Genet. 2019; 10: 438 DOI: 10.3389/fgene.2019.00438, 15 May 2019

  8. Lee, N.-H.; Park, S.-R.; Lee, J.W.; Lim, S.; Lee, S.-H.; Nam, S.; Kim, D.Y.; Hah, S.Y.; Hong, I.-S.; Lee, H.-Y. SERPINB2 Is a Novel Indicator of Cancer Stem Cell Tumorigenicity in Multiple Cancer Types. Cancers 2019, 11, 499. DOI: 10.3390/cancers11040499, 8 April 2019

  9. Jin-Hee Kim, Hyo Jin Eom, GyuTae Lim, Sungjin Park, Jinhyuk Lee, Seungyoon Nam, Yon Hui Kim, Jin-Hyun Jeong Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015. Br J Cancer 120, 488–498 (2019). DOI: 10.1038/s41416-018-0374-5, 22 February 2019

2018

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  1. Joo-Wook Kim, Jin Sook Lee, Jung Ho Kim, Joo-Won Jeong, Dae Ho Lee, and Seungyoon Nam Comparison of Microbiota Variation in Korean Healthy Adolescents with Adults Suggests Notable Maturity Differences OMICS: A Journal of Integrative Biology 2018 22:12, 770-778 DOI: 10.1089/omi.2018.0146, 27 November 2018

  2. Choi, J.-S.; Ryu, J.; Bae, W.-Y.; Park, A.; Nam, S.; Kim, J.-E.; Jeong, J.-W. Zingerone Suppresses Tumor Development through Decreasing Cyclin D1 Expression and Inducing Mitotic Arrest. Int. J. Mol. Sci. 2018, 19, 2832. DOI: 10.3390/ijms19092832, 19 September 2018

  3. Jae-Sun Choi, Woom-Yee Bae, Seungyoon Nam, and Joo-Won Jeong New Targets for Parkinson's Disease: Adhesion G Protein-Coupled Receptor B1 is Downregulated by AMP-Activated Protein Kinase Activation Omics: a journal of integrative biology 22(7):493-501 · July 2018 with 11 Reads DOI: 10.1089/omi.2018.0047, 1 July 2018

  4. Sungjin Park, SeongRyeol Moon, Ki young Lee, Ie Byung Park, Dae Ho Lee, Seungyoon Nam Urinary and Blood MicroRNA-126 and -770 are Potential Noninvasive Biomarker Candidates for Diabetic Nephropathy: A Meta-Analysis Cell Physiol Biochem 2018;46:1331-1340 DOI: 10.1159/000489148, 23 April 2018

  5. SeongRyeol Moon, Curt Balch, Sungjin Park, Jinhyuk Lee, Jiyong Sung, Seungyoon Nam Systematic Inspection of the Clinical Relevance of TP53 Missense Mutations in Gastric Cancer IEEE/ACM Transactions on Computational Biology and Bioinformatics PP(99):1-1 · March 2018 with 35 Reads DOI: 10.1109/TCBB.2018.2814049, 8 March 2018

  6. Sungjin Park, Seungyoon Nam A mutational co-occurrence network in gastric cancer based on an association index International Journal of Data Mining and Bioinformatics 20.1 (2018): 67-76 · DOI: 10.1504/IJDMB.2018.092159, 7 June 2018

  7. Sungjin Park, Seungyoon Nam sleBioRepo: a gene expression compendium in systemic lupus erythematosus International Journal of Data Mining and Bioinformatics, 2018 Vol.21 No.4, pp.365 - 375 DOI: 10.1504/IJDMB.2018.098947, January 2018

2017

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  1. Sungjin Park ; Seungyoon Nam, A mutational co-occurrence network of a stomach adenocarcinoma using an association index, 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Kansas City, MO, 2017, pp. 1782-1786, doi: 10.1109/BIBM.2017.8217931., November 2017

  2. Sungjin Park, Seungyoon Nam A combinational logic network based on binarised gene expression in gastric cancer International Journal of Data Mining and Bioinformatics 17(3):206 · July 2017 with 12 Reads DOI: 10.1504/IJDMB.2017.085279, 25 July 2017

  3. Min-Seok  Kwon, Seungyoon  Nam, Sungyoung  Lee, Young  Zoo  Ahn, Hae Ryung Chang, Yon Hui Kim and Taesung Park CANcer-specific Evaluation System (CANES): A high-accuracy platform, for preclinical single/multi-biomarker discovery Oncotarget 8(41) · July 2017 with 71 Reads DOI: 10.18632/oncotarget.19270, 15 July 2017

  4. Park, Sungjin & Nam, Seungyoon. (2017). A combinational logic network based on binarised gene expression in gastric cancer. International Journal of Data Mining and Bioinformatics. 17. 206. 10.1504/IJDMB.2017.10006245. DOI: 10.1504/IJDMB.2017.085279, July 2017 

  5. Seungyoon Nam Cancer Transcriptome Dataset Analysis: Comparing Methods of Pathway and Gene Regulatory Network-Based Cluster Identification Omics A Journal of Integrative Biology 21(4):217-224 · April 2017 with 41 Reads DOI: 10.1089/omi.2016.0169, 1 April 2017

  6. Seungyoon Nam, Jun-Won Chung, Jun-Young Yang WNT5A Correlates with Clinicopathological Characteristics in Gastric Cancer: a Meta-Analysis Cell Physiol Biochem 2017;41:33-40, DOI: 10.1159/000455934, 17 January 2017

  7. Seungyoon Nam Databases and tools for constructing signal transduction networks in cancer BMB Rep. 2017; 50(1): 12–19. · August 2016 with 47 Reads DOI: 10.5483/BMBRep.2017.50.1.135, 31 January 2017

  8. Bo Hyun Kim, Yeon-Su Lee, Byung Chul Kim, Aesun Shin, Jin Sook Kim, Seung-Hyun HongJung-Ah Hwang, Jung Ahn Lee, Seungyoon Nam, Sung Hoon Lee, Jong Bhak, Joong-Won Park Association of SLC15A2 genomic variation with the response to sorafenib treatment: Whole-genome analysis in patients with hepatocellular carcinoma. Journal of Clinical Oncology 33(3_suppl):308-308 · January 2015 DOI: 10.1200/jco.2015.33.3_suppl.308, 31 January 2017

  9. Sungjin Park, Seungyoon Nam Combinational logic network for digitally coded gene expression of gastric cancer  Conference: Conference: 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), DOI: 10.1109/BIBM.2016.7822788, 19 January 2017

2016

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  1. Hae Ryung Chang, Seungyoon Nam, Jinhyuk Lee, Jin-Hee Kim, Hae Rim Jung, Hee Seo  Park, Sungjin Park, Young Zoo Ahn, Iksoo Huh,  Curt Balch, Ja-Lok Ku, Garth Powis, Taesung Park, Jin-Hyun Jeong, Yon Hui Kim Systematic approach identifies RHOA as a potential biomarker therapeutic target for Asian gastric cancer Oncotarget 7(49) · October 2016 with 195 Reads DOI: 10.18632/oncotarget.12963, 28 October 2016

  2. Sang Jae Lee, Jang‐Sik Choi, Byeong‐Gu Han, Hyoun Sook Kim, Ho‐Juhn Song, Jaekyoo Lee Seungyoon Nam, Sung‐Ho Goh, Jung‐Ho Kim, Jong Sung Koh, Byung Il Lee Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: Structural insights for design of anticancer drugs FEBS Journal 283(19) · August 2016 with 85 Reads DOI: 10.1111/febs.13831, 6 October 2016

  3. Sungjin Park, Jinhyuk Lee, Yon  Hui  Kim, Jaheun Park, Jung-Woog Shin & Seungyoon Nam Clinical Relevance and Molecular Phenotypes in Gastric Cancer, of TP53 Mutations and Gene Expressions, in Combination With Other Gene Mutations Scientific Reports volume 6, Article number: 34822 (2016) DOI: 10.1038/srep34822, 6 October 2016

  4. Hyun Ji Kim, Gyeoung JinKang, Eun Ji Kim, Mi KyungPark, Hyun JungByun, SeungyoonNam, Ho Lee, Chang Hoon Lee Novel effects of sphingosylphosphorylcholine on invasion of breast cancer: Involvement of matrix metalloproteinase-3 secretion leading to WNT activation Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1862(9) · May 2016 with 59 Reads DOI: 10.1016/j.bbadis.2016.05.010, 20 May 2016

  5. Hae Ryung Chang, Hee Seo Park, Young Zoo Ahn, Seungyoon Nam, Hae Rim Jung, Sungjin Park, Sang Jin Lee, Curt Balch, Garth Powis, Ja-Lok Ku and Yon Hui Kim Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems BMC Cancer 16(1) · March 2016 with 34 Reads DOI: 10.1186/s12885-016-2232-2, 09 March 2016

2016 이전

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  1. Sungjin Park, Seok Jong Yu, Yongseong Cho, Curt Balch, Jinhyuk Lee, Yon Hui Kim, and Seungyoon Nam Network Comparison of Inflammation in Colorectal Cancer and Alzheimer's Disease BioMed Research International 2015(9) · February 2015 with 57 Reads DOI: 10.1155/2015/205247, 26 Jul 2015

  2. Yeon-Su Lee, Bo Hyun Kim, Byung Chul Kim, Aesun Shin, Jin Sook Kim, Seung-Hyun Hong, Jung-Ah Hwang, Jung Ahn Lee, Seungyoon Nam, Sung Hoon Lee, Jong Bhak, Joong-Won Park SLC15A2 genomic variation is associated with the extraordinary response of sorafenib treatment: Whole-genome analysis in patients with hepatocellular carcinoma Oncotarget 6(18) · April 2015 with 203 Reads DOI: 10.18632/oncotarget.3758, 22 April 2015 

  3. Hae Ryung Chang, Seungyoon Nam,Myeong-Cherl Kook, Kyung-Tae Kim, Xiuping Liu,Hui Yao, Hae Rim Jung, Robert Lemos Jr, Hye Hyun Seo, Hee Seo Park, Youme Gim,Dongwan Hong, Iksoo Huh,Young-Woo Kim,Dongfeng Tan,Chang-Gong Liu,Garth Powis,Taesung Park,Han Liang,Yon Hui Kim HNF4 is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer Gut 65(1):19-32 · January 2016 with 253 Reads DOI: 10.1136/gutjnl-2014-307918, 21 November 2014

  4. Youme Gim, Hee Seo Park, Hae Rim Jung, Hae Ryung Chang, Seungyoon Nam, Yong Doo Choi, Ja-Lok Ku and Yon Hui Kim Abstract 2783: Variability of HER2 expression between in vitro and in vivo models within gastric cancer cell lines Cancer Research 74(19 Supplement):2783-2783 · October 2014 with 2 Reads DOI: 10.1158/1538-7445.AM2014-2783, October 2014

  5. Hae Ryung Chang, Seungyoon Nam, Myeong-Cherl Kook, Hee Seo Park, Hae Rim Jung, Youme Gim, Han Liang, Garth Powis and Yon Hui Kim Abstract 1781: Identification of focal adhesion and actin cytoskeleton regulation family genes as druggable target for gastric cancer Cancer Research 74(19 Supplement):1781-1781 · October 2014 with 4 Reads DOI: 10.1158/1538-7445.AM2014-1781, October 2014

  6. Seungyoon Nam, Hae Ryung Chang, Hae Rim Jung, Youme Gim, Nam Youl Kim, Regis Grailhe, Haeng Ran Seo, Hee Seo Park, Curt Balch, Jinhyuk Lee, Inhae Park, So Youn Jung, Kyung-Chae Jeong, Garth Powis, Han Liang, Eun Sook Lee, Jungsil Ro, Yon Hui Kim A pathway-based approach for identifying biomarkers of tumor progression to trastuzumab-resistant breast cancer Cancer letters 356.2 (2015): 880-890, DOI: 10.1016/j.canlet.2014.10.038, 30 October 2014

  7. Hui Zeng, Xue-Bin Wang, Ning-Hua  Cui, Seungyoon Nam, Tuo Zeng, Xinghua Long Associations between AT-rich Interactive Domain 5B gene Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia: a Meta-analysis Asian Pac J Cancer Prev, 15 (15), 6211-6217 · August 2014 with 80 Reads DOI: 10.7314/APJCP.2014.15.15.6211 · Source: PubMed, 

  8. SeonJoo Ahn, GyuTae Lim, Seungyoon Nam, Jinhyuk Lee Structural Modeling of Vpu from HIV-1 based on Solid-State NMR Observables Chemical Physics Letters 599 · April 2014 with 12 Reads DOI: 10.1016/j.cplett.2014.03.033, 18 April 2014

  9. Nam S, Ryu H, Son W-J, Kim YH, Kim KT, Balch C, Nephew KP, Lee J, Mg2+ Effect on Argonaute and RNA Duplex by Molecular Dynamics and Bioinformatics Implications, PLoS ONE 9(10): e1097, (2014 Oct 17 published online) DOI: 10.1371/journal.pone.0109745

  10. Park IH, Kang JH, Lee KS, Nam S, Ro J, Kim JH Identification and clinical implications of circulating microRNAs for estrogen receptor-positive breast cancer Tumor Biology 35.12 (2014): 12173-12180, DOI: 10.1007/s13277-014-2525-5, 03 September 2014

  11. Hui Z, Fang C, Nam S, Cai Q, Long X The Clinicopathological Significance of MicroRNA-155 in Breast Cancer: A Meta-Analysis BioMed research international 2014 DOI: 10.1155/2014/724209, 03 August 2014

  12. Kwon C, Tak H, Rho M, Chang HR, Kim YH, Kim KT, Balch C, Lee EK, Nam S+, Detection of PIWI and piRNAs in the mitochondria of mammalian cancer cells, Biochemical and biophysical research communications 446.1 (2014): 218-223, DOI: 10.1016/j.bbrc.2014.02.112, 28 March 2014

  13. Nam S#, Chang HR#, Kim K-T, Kook M-C, Hong D, Kwon C, Jung HR, Park HS, Powis G, Liang H, Park T, Kim YH, PATHOME: an algorithm for accurately detecting differentially expressed subpathways, Oncogene 33.41 (2014): 4941, DOI: 10.1038/onc.2014.80, 31 March 2014

  14. Lee SJ, Joung JY, Yoon H, Kim JE, Park WS, Seo HK, Chung J, Hwang JA, Hong SH, Nam S, Park S, Kim J, Lee KH, Lee YS, Genetic variations of α-methylacyl-CoA racemase are associated with sporadic prostate cancer risk in ethnically homogenous Koreans,  BioMed research international 2013 (2013)., DOI: 10.1155/2013/394285, 07 Dec 2013

  15. Nam S+ Non-coding RNAs and Bioinformatics, Communications of the Korean Institute of Information Scientists and Engineers, 31:77-81, 2013 (published 16th Aug 2013) (in Korean)(+corresponding author)

  16. Antoon JW, Martin EC, Lai R, Salvo VA, Tang Y, Nitzchke AM, Elliott S, Nam SY, Xiong W, Rhodes LV, Collins-Burow B, David O, Wang G, Shan B, Beckman BS, Nephew KP, Burow ME, MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesis, PLoS One 8.8 (2013): e69291, DOI: 10.1371/journal.pone.0069291, 9 August 2013

  17. Hae Ryung Chang, Seungyoon Nam, Hae Rim Jung, ChangHyuk Kwon, Hye-Hyun Seo, Frances S. Sung, Hee Seo Park, Taesung Park and Yon Hui Kim Abstract 5540: Crosstalk between Wnt and AMPK pathway in Asian gastric cancer by metformin. Cancer Research 73(8 Supplement):5540-5540 · August 2013 with 2 Reads DOI: 10.1158/1538-7445.AM2013-5540, April 2013

  18. Han JY, Lee YS, Shin ES, Hwang JA, Nam S, Hong SH, Chang HY, Kim JY, Yoon SJ, Lee JS, A genome-wide association study of survival in small cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy, The pharmacogenomics journal 14.1 (2014): 20, DOI: 10.1038/tpj.2013.7, 12 March 2013

  19. Antoon JW, Mitzchke AM, Martin EC, Rhodes LV, Nam S, Wadsworth S, Salvo VA, Elliott S, Collins-Burow B, Nephew KP, Burow ME, Inhibition of p38 mitogen-activated protein kinase alters microRNA expression and reverses epithelial-to-mesenchymal transition, International Journal of Oncology, 42(4):1139-1150, 2013, DOI: 10.3892/ijo.2013.1814, 8 February 2013

  20. Hyungro Lee, Youngik Yang, Heejoon Chae, Seungyoon Nam, Donghoon Choi, Patanachai Tangchaisin, Chathura Herath, Suresh Marru, Kenneth P. Nephew and Sun Kim BioVLAB-MMIA: A cloud environment for microrna and mRNA integrated analysis (MMIA) on amazon EC2 IEEE transactions on nanobioscience 11(3):266-72 · September 2012 with 129 Reads DOI: 10.1109/TNB.2012.2212030 · Source: PubMed, 10 September 2012

  21. Jieun Lee,Sung-Ho Goh,Naaleum Song, Jung-Ah Hwang, Seungyoon Nam, Ju Choi, AesunShin, In-Hoo Kim, Mi-Ha Ju, Jin Sook Jeong, Yeon-Su Lee Overexpression of IFITM1 Has Clinicopathologic Effects on Gastric Cancer and Is Regulated by an Epigenetic Mechanism The American Journal Of Pathology 181(1):43-52 · May 2012 with 113 Reads DOI: 10.1016/j.ajpath.2012.03.027

  22. Nam S+, Xinghua L, Kwon C, Kim S, Nephew KP, An integrative analysis of cellular contexts, miRNAs and mRNAs reveals network clusters associated with antiestrogen-resistant breast cancer cell, BMC Genomics, 13:732, 2012, DOI: 10.1186/1471-2164-13-732, 27 December 2012

  23. Nam S#, Lee J#, Goh SH, Hong SH, Song N, Jang SG, Choi IJ, Lee YS, Differential gene expression pattern in early gastric cancer by an integrative systematic approach, International Journal of Oncology, 41(5):1675-82, 2012, DOI: 10.3892/ijo.2012.1621, 6 September 2012 

  24. Antoon JW, Lai R, Struckhoff AP, Nitschke AM, Elliott S, Martin EC, Rhodes LV, Nam S, Salvo VA, Shan B, Beckman BS, Nephew KP, Burow ME Altered Death Receptor Signaling Promotes Epithelial-to-Mesenchymal Transition and Acquired Chemoresistance, Scientific reports 2 (2012): 539, DOI: 10.1038/srep00539, 27 July 2012

  25. Balch C#, Naegeli K#, Nam S#, Ballard B, Hyslop A, Melki C, Reilly E, Hur M-W, Nephew K. A Unique Histone Deacetylase Inhibitor Alters MicroRNA Expression and Signal Transduction in Chemoresistant Ovarian Cancer Cells, Cancer biology & therapy 13.8 (2012): 681-693, DOI: 10.4161/cbt.20086, 01 June 2012

  26. Nam S+, Park T+ Pathway-Based Evaluation in Early Onset Colorectal Cancer Suggests Focal Adhesion and Immunosuppression along with Epithelial-Mesenchymal Transition, PLoS ONE, 7:e31685, 2012, DOI: 10.1371/journal.pone.0031685, 9 April 2012

  27. Rhodes LV, Nitschke AM, Segar HC, Martin EC, Driver JL, Elliott S, Nam SY, Li M, Nephew KP, Burow ME, and Collins-Burow BM. The histone deacetylase inhibitor trichostatin A alters microRNA expression profiles in apoptosis-resistant breast cancer cells, Oncology Reports, 27:10-16, 2012, DOI: 10.3892/or.2011.1488, 4 October 2011 

  28. Foley J, Nickerson N, Nam S, Allen KT, Gilmore JL, Nephew KP, and Riese DJ. EGFR Signaling in Breast Cancer: Bad to the Bone. Seminars in cell & developmental biology. Vol. 21. No. 9. Academic Press, 2010, DOI: 10.1016/j.semcdb.2010.08.009, 9 September 2010

  29. Nam S, Li M, Choi K, Balch C, Kim S, Nephew KP. MicroRNA and mRNA integrated analysis (MMIA): a web tool for examining biological functions of microRNA expression, Nucleic Acids Res, 37:W356-W362 2009, DOI: 10.1093/nar/gkp294, 06 May 2009

  30. Lee KE#, Nam S#, Cho EA#, Seong I, Limb JK, Lee S, Kim J. Identification of direct regulatory targets of the transcription factor Sox10 based on function and conservation, BMC genomics 9.1 (2008): 408, DOI: 10.1186/1471-2164-9-408, 11 September 2008

  31. Nam S#, Kim B#, Shin S, Lee S. miRGator: an integrated system for functional annotation of microRNAs. Nucleic acids research 36.suppl_1 (2007): D159-D164, DOI: 10.1093/nar/gkm829, 16 October 2007

  32. Kim B, Lee HJ, Choi HY, Shin Y, Nam S, Seo G, Son D, Jo J, Kim J, Lee J, Kim J, Kim K, Lee S. Clinical Validity of the Lung Cancer Biomarkers Identified by Bioinformatics Analysis of Public Expression Data. Cancer research 67.15 (2007): 7431-7438, DOI: 10.1158/0008-5472.CAN-07-0003, 25 May 2007

  33. Lee Y, Lee Y, Kim B, Shin Y, Nam S, Kim P, Kim N, Chung WH, Kim J, Lee S. ECgene: an alternative splicing database update. Nucleic acids research 35.suppl_1 (2006): D99-D103, DOI: 10.1093/nar/gkl992, 28 November 2006

  34. Nam S, Lee SM, Lee SH, Shin S, Park T. Bayesian Hierarchical Models for Serial Analysis of Gene Expression. VLDB Workshop on Data Mining and Bioinformatics. Springer, Berlin, Heidelberg, 2006, DOI: 10.1007/11960669_4, 

  35. Kim N, Kim P, Nam S, Shin S, Lee S. ChimerDB—a knowledgebase for fusion sequences. Nucleic Acids Res, 34:D21-D24, 2006, DOI: 10.1093/nar/gkj019, 01 January 2006

  36. Nam S, Kim Y, Kim P, Kim VN, Shin S, Lee S. Prediction of mammalian microRNA targets - Comparative genomics approach with longer 3' UTR databases. Genomics & Informatics 3.3 (2005): 53-62, 1 September 2005

International Conferences (Full papers accepted after reviews, not abstracts)

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  1. Hyungro Lee, Youngik Yang, Heejoon Chae, Seungyoon Nam, Donghoon Choi, Patanachai Tangchaisin, Chathura Herath, Suresh Marru, Kenneth Nephew, and Sun Kim, BioVLAB-MMIA: A Reconfigurable Cloud Computing Environment for microRNA and mRNA Integrated Analysis, accepted in the regular paper track in IEEE International Conference on Bioinformatics and Biomedicine 2011 (IEEE BIBM 2011), Atlanta, GA

Posters

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  1. Kwon C, Tak H, Rho M, Chang HR, Kim YH, Kim KT, Lee EK, Balch C, Nam S, Detection of PIWI-piRNAS in the mitochondria of human normal and cancer cells, AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA

  2. Chang HR, Nam S, Jung HR, Kwon C, Seo H-H, Sung FS, Park HS, Park T, Kim YH, Crosstalk between Wnt and AMPK pathway in Asian gastric cancer by metformin, AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC

  3. Nam S Identification of relevant subpathways from molecular pathways in gene expression data by a probabilistic approach, IEEE International Conference on Bioinformatics and Biomedicine, 18-21 Dec 2010, Hong Kong Accepted posters (P232)

  4. Nam S, Li M, Choi K, Balch C., Kim S, Nephew KP. MicroRNA and mRNA Integrated Analysis (MMIA): A Web Tool for Examining Biological Functions of MicroRNA Expression. The annual IU Simon Cancer Center’s Cancer Research Day, 2009, Indianapolis, U.S., Abstract book

  5. Balch C, Naegeli K, Nam S, Thomson JM, Reilly E, Chen C-S, Hammond S, Nephew KP. Differential transcriptional regulation of microRNAs, in ovarian cancer cells, by two distinct hydroxamic acid histone deacetylase inhibitors. The annual IU Simon Cancer Center’s Cancer Research Day, 2009, Indianapolis, U.S., Abstract book

  6. Nam S, Son W-J, Lee S, Shin S. Asymmetry of mature miRNA selection: insight from physicochemical approach. ISMB 2008, Toronto, Canada Abstract ISMB 2008 Abstract list

  7. Cho EA, Nam S, Roh J, Seong IJ, Lee S, Kim J. Function- and conservation-based identification of direct regulatory targets of the transcription factor Sox10. FAOBMB 2007, Seoul, Korea

  8. Lee YS, Lee YH, Kim B, Shin Y, Nam S, Kim P, Kim N, Chung W-H, Kim J, Lee S. ECgene: an alternative splicing database update. FAOBMB 2007, Seoul, Korea

  9. Nam S, Kim B-H, Shin S, Lee S. Identification of novel intronic microRNAs by an iterative ensemble SVM method. FAOBMB (Federation of Asian and Oceanian Biochemists and Molecular Biologists) 2007 (27 – 31 May 2007), Seoul, Korea

  10. Nam S+, Kim B+, Shin S, Lee S miRGator : an integrated system for functional annotation of microRNAs. CMDDS 2007, Seoul, Korea (+ joint first authors)

  11. Nam S, Kim B-H, Shin S, Lee S. Identification of novel intronic microRNAs by an iterative ensemble SVM method. ISMB 2007, Vienna, Austria Abstract

  12. Nam S, Kim B, Lee S. Genome-wide identification of intronic microRNAs by computational approach. BIOINFO 2006(KSBI), Pohang, Korea

  13. Nam S, Lee SM, Lee SH, Shin S, Park T. Bayesian Hierarchical Models for Serial Analysis of Gene Expression. VDMB 2006, Seoul, Korea

  14. Jeong H, Nam S, Sung I, Lee S, Kim J. Function- and conservation-based identification of direct regulatory targets of transcription factor Sox10. KSBMB 2005, Seoul, Korea

  15. Kim B+, Nam S+, Yu U, Kim S, Shin S, Lee S. ECprofiler: candidate gene search system for ECgene and UniGene. KSBMB 2005, Seoul, Korea (+ joint first authors)

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